ISSN 1392-0146
ISSN 2029-0578 (online)
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2007 m. Nr. 4
Anomalous phospholipid subdiffusion in compartmentalized cell membrane and the mathematical model of the time-dependent diffusion coefficient
Paulius MIŠKINIS
Recent experimental data on an anomalous diffusion of phospholipids in compartmentalized cell membrane are analysed. A new mathematical model of passive transport with the time-dependent diffusion coefficient is proposed. The model with the step-type asymptotical dependence of the diffusion coefficient is applied to a concrete example, and a correspondence between the experimental and theoretical results is shown. The random distribution of immobilized obstructions as well as the membrane skeleton meshwork offer a theoretical basis for modifying the available models of transport and thus for refining the diffusion model. The experimentally obtained time-dependend coefficient of diffusion is shown to agree with the proposed theoretical model.
Keywords: passive transport, the first Fick’s law, mathematical modeling
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