Chemija / Chemistry
 ISSN 0235-7216 ISSN 2424-4538 (online) |
2012 m. Nr. 1 Synthesis and structure of new 1,3-disubstituted 5-oxopyrrolidine derivatives
A novel series of 1,3-disubstituted pyrrolidinone derivatives with aromatic, hydrazone, azole, diazole and triazole moieties has been prepared from 3-carbohydrazides of 1-phenyl-5-oxopyrrolidine and 1-(4-bromophenyl)-5-oxopyrrolidine. The structure of all the study compounds has been confirmed on the basis of NMR, IR, mass spectra, and elemental analyses data. In some cases, molecular modeling was used for determining the spatial structure.
Keywords: 5-oxo-1-phenylpyrrolidine-3-carbohydrazides, cyclization, azoles, isomerism, NMR spectroscopy |
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